Postdoctoral researcher – hematopoietic stem cell based gene therapy – Paris area, France

Postdoctoral researcher – hematopoietic stem cell based gene therapy – Paris area, France
A postdoctoral position is available in the therapeutic genomic editing team under the direction of Mario Amendola in Genethon, biopark of Evry, France.
Our laboratory is focused in developing effective and safe genome editing and gene therapy strategies for the treatment of human diseases. In particular, we are interested in genetically engineering hematopoietic stem and progenitor cells: 1) for treating and gaining a better understanding of blood disorders, in particular sickle-cell disease, β-thalassemia and hemophilia; 2) as therapeutic delivery vehicles, due to the ability of their progeny to extensively home to many tissues, including the central nervous system.
Candidates should be able to work independently and interactively in a team setting, be responsible, organized and have a great work capacity and enthusiasm for research.
Prior experience in hematology is essential, familiarity with molecular and cellular biology an advantage. Candidates should have at least one first author publication in a good quality journal and excellent communication skills in spoken and written English.
Host institute
Genethon is a non-profit biotherapy R&D organization dedicated to the development of gene therapy products for rare human diseases led by Dr Fulvio Mavilio. To achieve this aim, Genethon partners with two universities and the INSERM research unit UMR_S951-INTEGRARE ( and it hosts several laboratories with diverse fields of expertise, all exploiting gene-based technologies to investigate biological systems and pathologies of genetic origin and to design gene therapy treatments mainly for: i) blood and immune disorders, ii) neuromuscular disorders, iii) liver and metabolic disorders.
Genethon offers several high quality core facilities and infrastructure including:
 in vitro and in vivo therapeutic testing platform: a functional evaluation platform (including ultrasound testing), an imaging-cytometry platform (confocal, macroconfocal and biophotonic microscopy, imaging flow cytometry), a viral vector research facility (for LV, RV and AAV), tools and experience in molecular and physiopathological examination of isolated living cells; a histology department;
 the largest DNA and cell bank in Europe for human genetic disorders
– Salary: according to experience
– 2 years full-time contract (renewable, based on performance)
– Starting date: flexible, from June 2016
How to apply
To apply, please send an email to Dr. Mario Amendola (
The application should include:
 a research interest letter
 a curriculum vitae
 at least two references (names and contact information)
Documents should be sent as a single pdf file no later than 15th of June 2016
1 rue de l’Internationale
91002 Evry Cedex