Vacancy: GTIMC Process Development Technician

University of Sheffield

GTIMC Process Development Technician


Job reference number: UOS034902

Contract type: Fixed term for four years

Faculty: Faculty of Medicine, Dentistry and Health

Department: Gene Therapy Innovation & Manufacturing Centre (GTIMC)

Location: Gene Therapy Innovation & Manufacturing Centre (GTIMC)

Salary: Grade 6 £28,762- £33,314 per annum. Potential to progress to £36,386 per annum through sustained exceptional contribution


The Sheffield Gene Therapy Innovation and Manufacturing Centre (GTIMC) is one of three cutting-edge hubs in the UK dedicated to advancing the clinical development of new genetic treatments options for millions of patients with life-threatening diseases.


Gene therapy is a promising treatment option for a number of diseases that currently have no other cures including inherited disorders


The Sheffield Hub, which is the first in the north of England, is part of an £18 million network created by LifeArc and the Medical Research Council (MRC), with support from the Biotechnology and Biological Sciences Research Council (BBSRC)


The GTIMC is located on the site of the University of Sheffield’s Innovation District close to the centres of Sheffield and Rotherham and within easy reach of major transportation corridors and regional shopping and entertainment complexes.


The centre will include a cutting-edge GMP (good manufacturing practice) facility that will support gene therapy projects emerging from universities across the UK.


The facility will utilise highly efficient processes to manufacture clinical grade adeno-associated viruses (AAV) and provide all the necessary quality assurance, regulatory certification and governance for human trials at Advanced Therapies Treatment Centres and NHS hospital sites.


The Process Development Technicians will support the technology transfer of AAV production methods to the GTIMC from collaborator sites. Once these transfers are complete the post holder will work with GTIMC process development scientists to scale up these processes. In addition the post holder will perform day to day vector manufacturing and process development activities, adhering to the relevant Good Manufacturing Practice (GMP) requirement.


We’re one of the best not-for-profit organisations to work for in the UK. The University’s Total Reward Package includes a competitive salary, a generous Pension Scheme and annual leave entitlement, as well as access to a range of learning and development courses to support your personal and professional development.


We build teams of people from different heritages and lifestyles from across the world, whose talent and contributions complement each other to greatest effect. We believe diversity in all its forms delivers greater impact through research, teaching and student experience.


To find out what makes the University of Sheffield a remarkable place to work, watch this short film: www.youtube.com/watch?v=7LblLk18zmo, and follow @sheffielduni and @ShefUniJobs on Twitter for more information.


Closing date: 10 November 2022.


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