Resolution Therapeutics is a biotechnology company developing macrophage cell therapies for chronic liver disease. Founded in 2019 by Professor Stuart Forbes and Professor John Campbell from the University of Edinburgh in collaboration with Syncona, the company is pioneering the development of macrophages to treat inflammation and resolve fibrosis.
The company’s lead product is an autologous engineered macrophage therapy designed to treat liver cirrhosis. Chronic liver disease is the only chronic disease still on the rise in western countries, affecting millions of people worldwide. For patients with end-stage liver disease (cirrhosis) the only therapeutic option is liver transplantation, a complex surgical procedure limited by complications and a shortage of donors.