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Genetic therapies for retinal disease

J Kapetanovic(1)

1:University of Oxford

Inherited retinal diseases (IRDs) are the leading cause of blindness certification in the working age. Transformational advances have occurred in recent years in our ability to genetically diagnose these conditions as well as in our understanding of pathogenic mechanisms and the range of variability seen in each disorder. The vast majority are still untreatable. We currently have one licensed gene therapy treatment Luxturna for one type of RPE65-related retinal and several more are on the horizon. This talk covers the current landscape and likely future therapies including novel delivery methods using robotics. 

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